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In 2018, there are an estimated 2.1 million new cases and nearly 1.7 million deaths, while the incidence of lung cancer and mortality ranks first among all tumors in China ( In recent years, some researchers have discovered that ferroptosis is suppressed in lung cancer cells

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51 The most prominent metabolic function of SAM is its role as a methyl donor, with over 90% of the SAM produced being consumed in methylation reactions